Pharmacokinetics Simulator

One-compartment oral dosing model. Adjust parameters and see how plasma concentration changes over time.

Tmax

2.56hr

Time to peak

Cmax

24.78mg/L

Peak concentration

AUC

320.0mg·hr/L

Total exposure

t½

6.93hr

Half-life

C(t) = F·D·k_a / V·(k_a−k_e) · (e^−k_et − e^−k_at)

Figure 2. Simulated plasma concentration–time profile. One-compartment oral dosing model with first-order absorption and elimination.

Custom parameters · F=0.8 · D=400mg · V=10L · k_a=1/hr · k_e=0.1/hr

Bioavailability (F)

Dose (D)

Volume of Distribution (V)

Absorption Rate (kₐ)

1/hr

Elimination Rate (kₑ)

1/hr

Half-life (t½)

MEC

mg/L

Toxic

mg/L

Simulation Duration (T)

Sanity Check

Overlay modified curves to verify expected PK behavior

Multiple Dose

Show drug accumulation from repeated dosing